Reducing opioid dose via targeted nociception monitoring
نویسندگان
چکیده
منابع مشابه
Ultra-low-dose opioid antagonists enhance opioid analgesia while reducing tolerance, dependence and addictive properties
Ultra-low-dose opioid antagonists, when combined with opiates, increase the analgesic efficacy and duration of analgesia of the opiate. This enhanced and prolonged analgesia was recently demonstrated in a 350-patient Phase II clinical trial of Oxytrex, a novel drug candidate that combines oxycodone with an ultra-low dose of the opioid antagonist naltrexone. Extensive preclinical data also show ...
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INTRODUCTION Traditionally, opioids have been the cornerstone of therapy for patients suffering from cancer pain, regardless of the potential to develop opioid tolerance. In chronic pain patients who experience worsening pain despite increasing doses of opioids, the clinical role of opioid-induced hyperalgesia is gaining more recognition. CASE Presented here is the case of a 56-year-old man w...
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ژورنال
عنوان ژورنال: Deutsches Aerzteblatt Online
سال: 2020
ISSN: 1866-0452
DOI: 10.3238/arztebl.2020.0831